Ferrand User
You are required to completed the following materials:
Required Resources
Commentary
- Week 5 Slides with Videos
- Week 5 Lecture – Somatosensory Systems
- Week 5 Lecture – Taste and Smell
- Module 5: Central Neurons: Receiving Inputs, Processing Information, Directing behavior
- Module 6: Plasticity: Flexibility in the System (focus on Topic 4)
Week 5 Helpful Resources (Optional Readings and Videos)
Somatosensory System
a. NervousSystemUnit14_AP_OLI (under Nervous System Chapters), Module 56 pp. 451-455
b. Tutorial on Receptors of the Skin
c .Visual System
NervousSystemUnit14_AP_OLI (under Nervous System Chapters; or found under oli/cmu/edu Anatomy and Physiology course—registration required), Module 56 pp. 458-464
d. Tutorial on Receptive Fields in the Retina
Information Processing in the Retina
e. Tutorial on Visual Pathways in the Human Brain
Visual Pathways in the Human Brain
f. Auditory System
NervousSystemUnit14_AP_OLI (under Nervous System Chapters, Module 56 pp. 465-470
g. Vestibular Sense
Tutorial on Vestibular Sense
h .Smell and Taste
NervousSystemUnit14_AP_OLI (under Nervous System Chapters), Module 56 pp. 471-476
Videos
Vid1. Physiological Mapping of Visual Cortical Neurons (Nobel prize-winning studies of Hubel and Wiesel)
Hubel & Wiesel – Cortical Neuron – V1
Vid 2. These are recordings of the electrophysiological recordings of different types of visual cortical neurons.
How the Body Works: The Organs of Balance
How the Body Works: The Organs of Balance, Dan Izzo
[Website URL for all videos listed below is: http://www.interactive-biology.com/physiologyvideos/]Vid 3. A General Overview of How Senses Work
Interactive Biology #029, 3:04 minutes
Vid 4. How Eyes Work—An Introduction
Interactive Biology #030, 10:49 minutes
Vid 5. How Rods and Cones Respond to Light
Interactive Biology #031, 12:09 minutes
Vid. 6Visual Processing in the Retina
Interactive Biology #032, 11:33 minutes
V7. The Receptive Field of a Ganglion Cell
Interactive Biology #033, 7:12 minutes
V8. How Lateral Inhibition enhances Vidual Edges
Interactive Biology #034, 5:23 minutes
V9. On Center, Off Surround Ganglion Cells
Interactive Biology #035, minutes
V10. An Overview of the Mechanism of Hearing
Interactive Biology #036, 7:20 minutes
How Sound is Transferred to the Inner Ear
Interactive Biology #037, 11:36 minutes
How We Hear Different Pitches
Interactive Biology #038, 8:52 minutes
The Function of the Organ of Corti
Interactive Biology #039, 8:34 minutes
The Role of Hair Cells in Hearing
Module 3: Sensory Neurons: Getting Information into the System (week5)
Autism & Psychedelics
Barnes, N. M., & Sharp, T. (1999). A review of central 5-HT receptors and their function. Neuropharmacology, 38(8), 1083–1152. https://doi.org/10.1016/s0028-3908(99)00010-6
ID: A2-R1
5HT – Subtypes
5-HT1, 5-HT2, 5-HT3 and 5-HT7 Receptors and their Role in the Modulation of Pain Response in the Central Nervous System
Cortes-Altamirano, J. L., Olmos-Hernández, A., Jaime, H. B., Carrillo‐Mora, P., Bandala, C., Reyes-Long, S., & Alfaro-Rodríguez, A. (2018). Review: 5-HT1, 5-HT2, 5-HT3 and 5-HT7 Receptors and their Role in the Modulation of Pain Response in the Central Nervous System. Current Neuropharmacology, 16(2). https://doi.org/10.2174/1570159×15666170911121027
ID: A2-R2
5Ht – Psychedelics
Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264–355. https://doi.org/10.1124/pr.115.011478
ID: A2-R3
Serotonin G protein Coupled Receptors
Structure and Function of Serotonin G protein Coupled Receptors
McCorvy, J. D., & Roth, B. L. (2015). Structure and function of serotonin G protein-coupled receptors. Pharmacology & Therapeutics (Oxford), 150, 129–142. https://doi.org/10.1016/j.pharmthera.2015.01.009
ID: A2-R4
Depression (Not MDD)
What has serotonin to do with depression?
Cowen, P. J., & Browning, M. (2015b). What has serotonin to do with depression? World Psychiatry, 14(2), 158–160. https://doi.org/10.1002/wps.20229
ID: A2-R5
(MDD: Yes) Serotonin System
Rewiring of the Serotonin System in Major Depression
Vahid-Ansari, F., & Albert, P. R. (2021). Rewiring of the serotonin system in major depression. Frontiers in Psychiatry, 12. https://doi.org/10.3389/fpsyt.2021.802581
ID: A2-R6
Autism – ASD
Autism
Hodges, H., Fealko, C., & Soares, N. (2020). Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation. Translational pediatrics, 9(Suppl 1), S55–S65. https://doi.org/10.21037/tp.2019.09.09
Ploeger, A., & Galis, F. (2011). Evolutionary approaches to autism- an overview and integration. McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students, 13(2), 38.
Masi, A., DeMayo, M. M., Glozier, N., & Guastella, A. J. (2017). An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options. Neuroscience bulletin, 33(2), 183–193. https://doi.org/10.1007/s12264-017-0100-y
autism risk factors
Autism risk factors: genes, environment, and gene-environment interactions
Completed!
Chaste, P., & Leboyer, M. (2012). Autism risk factors: genes, environment, and gene-environment interactions. Dialogues in clinical neuroscience, 14(3), 281–292. https://doi.org/10.31887/DCNS.2012.14.3/pchaste
Pschedelics – 5HT2a
Psychedelics
The neural basis of psychedelic action
Completed!
Kwan, A. C., Olson, D. E., Preller, K. H., & Roth, B. L. (2022). The neural basis of psychedelic action. Nature neuroscience, 25(11), 1407–1419. https://doi.org/10.1038/s41593-022-01177-4
Structure of a Hallucinogen-Activated GQ-Coupled 5-HT2A serotonin receptor
Completed!
Kim, K., Che, T., Panova, O., DiBerto, J. F., Lyu, J., Krumm, B. E., Wacker, D., Robertson, M. J., Seven, A. B., Nichols, D. E., Shoichet, B. K., Skiniotis, G., & Roth, B. L. (2020). Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor. Cell, 182(6), 1574–1588.e19. https://doi.org/10.1016/j.cell.2020.08.024
Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways
López-Giménez, J. F., & González-Maeso, J. (2018). Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways. Current topics in behavioral neurosciences, 36, 45–73. https://doi.org/10.1007/7854_2017_478
Psychedelics and Consciousness: Distinctions, Demarcations, and Opportunities
Yaden, D. B., Johnson, M. W., Griffiths, R. R., Doss, M. K., Garcia-Romeu, A., Nayak, S., Gukasyan, N., Mathur, B. N., & Barrett, F. S. (2021). Psychedelics and Consciousness: Distinctions, Demarcations, and Opportunities. The international journal of neuropsychopharmacology, 24(8), 615–623. https://doi.org/10.1093/ijnp/pyab026
Neuropathy
Items Complete